Melanoma occurring during treatment with fingolimod for multiple sclerosis: a case report.

نویسندگان

  • Katrin Baumann Conzett
  • Isabel Kolm
  • Ilijas Jelcic
  • Jivko Kamarachev
  • Reinhard Dummer
  • Ralph Braun
  • Lars E French
  • Michael Linnebank
  • Günther F L Hofbauer
چکیده

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Sensory-Neural Hearing Loss as an Early Rebound Relapse after Fingolimod Cessation in Multiple Sclerosis

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Rebound of disease activity after withdrawal of fingolimod (FTY720) treatment.

BACKGROUND The oral sphingosine-1-phosphate receptor modulator fingolimod (FTY720) was recently approved for the treatment of relapsing-remitting multiple sclerosis. To date, data about a possible recurrence of disease activity after discontinuation of fingolimod treatment are scarce. OBJECTIVE To describe a patient who discontinued fingolimod treatment after a local malignant melanoma was di...

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Evaluation of the Incidence of Macular Edema in Patients with Multiple Sclerosis Treated with Fingolimod

Purpose: To determine the incidence of macular edema in patients with MS treated with 0.5 mg Fingolimod. Methods: In this prospective descriptive-analytic study a total of 115 patients were enrolled. Patients underwent an ophthalmologic examination before starting the treatment. In the fourth month after starting the treatment for each patient, regardless of whether or not being marked, the oph...

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Retinal hemorrhages following fingolimod treatment for multiple sclerosis; a case report

BACKGROUND Fingolimod is the first oral agent used for treatment of relapsing-remitting multiple sclerosis. Macular edema, but not retinal hemorrhage, is a well-known adverse effect of fingolimod treatment. To the best of our knowledge, this is the first case report of extensive retinal hemorrhages following fingolimod treatment. CASE PRESENTATION A 31-year-old male with relapsing-remitting m...

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Fingolimod in a patient with heart failure on the background of pulmonary arterial hypertension and coronary artery disease

BACKGROUND Fingolimod is the first oral immunomodulatory therapy approved for highly active relapsing remitting multiple sclerosis. Based on the distribution pattern of fingolimod interacting sphingosine-1-phosphat receptors in organism including immune system and cardiovascular system clinical monitoring of patients and evaluation of adverse events are recommended. Despite extensive data on ca...

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عنوان ژورنال:
  • Archives of dermatology

دوره 147 8  شماره 

صفحات  -

تاریخ انتشار 2011